Fig. 5
From: The glycosaminoglycan chains of perlecan regulate the perivascular fluid transport
Clearance of ovalbumin-Texas Red tracer (45 kDa) from the brain parenchyma into the deep cervical lymph nodes. A) Schematic timeline of tracer infusion into the brain parenchyma along the anterior/posterior (A/P), medial/lateral (M/L) and dorsal/ventral (D/V) axes and collection of the tissue samples. B) Illustrative images of the brain and deep cervical lymph nodes (dcLNs) from Hspg2+/+ and Hspg2∆3∆91 mice, with quantification (C-D, n = 7 mice per genotype). Scale bar, 1 mm (brain), 500 μm (dcLN). The statistical test used was the unpaired two-tailed t-test with Welch’s correction (C, D). ns, non-significant. Mean ± SEM